NSAIDS and Your Kidneys

What are NSAIDs?
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are part of a medication class that works to reduce inflammation, redness, swelling, pain, and fever. 

• Over the Counter (OTC):
  • Ibuprofen (Advil or Motrin, 200mg)
  • Naproxen (Aleve 220mg)
  • Aspirin (81-300mg)
• Prescription:
  • Diclofenac
  • Diflunisal
  • Etodolac
  • Fenoprofen
  • Flurbiprofen
  • Ibuprofen (400-800mg)
  • Indomethacin
  • Ketoprofen
  • Ketorolac
  • Mefenamic
  • Meloxicam
  • Nabumetone
  • Naproxen (500mg)
  • Oxaprozin
  • Piroxicam
  • Sulindac

Why are NSAIDs bad for the kidneys?
NSAIDs can cause the blood vessels to narrow as a result of reducing inflammation and swelling. This can cause an increase in blood pressure, damage the kidney tissue and structures, as well as reduce the flood flow to the kidneys. Over time, this can end up damaging the kidneys. Additionally, as you age, these drugs may have a stronger effect and doses may need to be reduced.

I have chronic kidney disease. What pain medication can I take?

• Acetaminophen is the preferred over the counter pain relief drug for those with Chronic Kidney Disease. 
• Other prescription pain medication should be approved by your nephrologist. 
• Other non-pharmacological pain interventions are available on a case-by-case basis.

Please consult with your nephrologist before starting any new pain medications or if you have questions regarding your prescriptions. As always, stay safe!

​Resources:
https://www.ncbi.nlm.nih.gov/books/NBK547742/
https://www.kidney.org/news/kidneyCare/winter10/MedicinesForPain


​​This website is for informational and educational purposes ONLY. While we strive for accurate, general medical information, this does not replace professional medical advice. Do not rely solely on this information. Please consult with your provider for more information regarding your specific needs. If you are experiencing a medical emergency, please call 9-1-1.